Eastern Panama Vacation Packages 2026 from $595

Eastern Panama flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Metro Hotel Panama

Bella Vista

$595

per person

Jan 7 - Jan 14

found 1 day ago

Roundtrip flight included

Port of Spain (POS) to Panama City (PTY)

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and airport shuttle. You'll appreciate the shopping center shuttle, coffee shop/cafe, and computer station.

Megapolis Hotel Panamá

San Francisco

$1,022

per person

Dec 3 - Dec 7

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.

Central Hotel Panama Casco Viejo

Casco Viejo

$1,486

per person

Jan 17 - Jan 23

found 10 hours ago

Roundtrip flight included

Port of Spain (POS) to Panama City (PTY)

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

La Concordia Boutique Hotel

Casco Viejo

Save 100% on your flight

$1,902

per person

Jan 7 - Jan 14

found 1 day ago

Roundtrip flight included

Port of Spain (POS) to Panama City (PTY)

This hotel features a bar/lounge, free WiFi in public areas, and a terrace. Families will appreciate barbecue grills and in-room childcare. Traveling on business? Take advantage of the express check-out, laundry service, and airport shuttle.

Hotel San Pedro de Taboga

$750

per person

Jan 24 - Jan 30

found 23 hours ago

Roundtrip flight included

Georgetown (GEO) to Panama City (PTY)

A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. A garden, luggage storage, and laundry facilities are also on offer.

Stay near popular Eastern Panama attractions

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

See properties

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as $595. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.